Description

3α-Hydroxycostunolide is a sesquiterpene lactone derivative, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique structural framework makes it a valuable intermediate for developing novel bioactive molecules and exploring structure-activity relationships. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies focused on anti-inflammatory, anticancer, and other therapeutic agent discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex natural product analogs and potential drug candidates.
• Biochemical Research: Used as a reference standard or probe in studies investigating sesquiterpene lactone biosynthesis, metabolism, and biological activity.
• Anti-inflammatory Agent Development: Explored for its potential as a lead compound or pharmacophore in the design of new anti-inflammatory therapeutics.
• Anticancer Research: Investigated for its cytotoxic properties and mechanisms of action against various cancer cell lines in preclinical studies.
• Natural Product Chemistry: Employed in the total synthesis, semi-synthesis, or structural modification of costunolide-related natural products.
• Academic & Industrial R&D: Essential for laboratories conducting advanced organic synthesis, medicinal chemistry, and pharmacological screening.

Basic Information

Product Name	3α-Hydroxycostunolide
CAS No.	18045-83-5
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.33 g/mol
Synonyms	3α-Hydroxycostunolide; 3α-Hydroxy-11,13-dihydrocostunolide; (3α,4α,5β,6α,7α,8α)-3-Hydroxy-4,5,6,7,8,8a-hexahydro-6-methyl-3,8-bis(methylene)azuleno[4,5-b]furan-2(3H)-one; Costunolide, 3α-hydroxy-; 3α-Hydroxy-4,5,6,7,8,8a-hexahydro-6-methyl-3,8-bis(methylene)azuleno[4,5-b]furan-2(3H)-one
EINECS	Contact for details

Quality Control

Our 3α-Hydroxycostunolide is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.