Description

4-(p-tert-Butylbenzyl)-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone is a high-purity, synthetic organic compound belonging to the ketone and piperazine derivative class. This specialized chemical serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block for research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Research & Development: Used as a building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Synthesis: Serves as a versatile reagent for constructing complex molecular architectures containing piperazine and aryl ketone moieties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-(p-tert-Butylbenzyl)-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone
CAS No.	17766-62-0
Molecular Formula	C25H34N2O4
Molecular Weight	426.55 g/mol
Synonyms	1-[4-(1,1-Dimethylethyl)phenyl]methyl-4-(3,4,5-trimethoxybenzoyl)piperazine; 4-(3,4,5-Trimethoxybenzoyl)-1-[[4-(tert-butyl)phenyl]methyl]piperazine; 1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-4-(3,4,5-trimethoxybenzoyl)piperazine; (3,4,5-Trimethoxyphenyl)[4-[[4-(1,1-dimethylethyl)phenyl]methyl]-1-piperazinyl]methanone; 4-(p-tert-Butylbenzyl)piperazino-3,4,5-trimethoxyphenyl ketone; 4-(4-tert-Butylbenzyl)piperazin-1-yl(3,4,5-trimethoxyphenyl)methanone
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Quality Control

Our 4-(p-tert-Butylbenzyl)-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.