Description

α-[4-(o-Chlorophenyl)-1-Piperazinyl]-3',4',5'-Trimethoxyacetophenone CAS NO 17755-62-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex piperazine-acetophenone hybrid structure. This compound is of significant value for its role as a key building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential antipsychotic and neuroleptic drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies targeting serotonin and dopamine receptor systems.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Biochemical Tool Compound: Utilized in preclinical studies to investigate neurological pathways and receptor binding mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for clinical trials.

Basic Information

Product Name	α-[4-(o-Chlorophenyl)-1-Piperazinyl]-3',4',5'-Trimethoxyacetophenone
CAS No.	17755-62-3
Molecular Formula	C21H25ClN2O4
Molecular Weight	404.89 g/mol
Synonyms	1-[4-(2-Chlorophenyl)piperazin-1-yl]-2-(3,4,5-trimethoxyphenyl)ethanone; 2-(3,4,5-Trimethoxyphenyl)-1-[4-(2-chlorophenyl)-1-piperazinyl]ethanone; o-Chlorophenylpiperazinyl Trimethoxyacetophenone; α-(4-(2-Chlorophenyl)-1-piperazinyl)-3,4,5-trimethoxyacetophenone; CAS 17755-62-3
EINECS	Contact for details

Quality Control

Our α-[4-(o-Chlorophenyl)-1-Piperazinyl]-3',4',5'-Trimethoxyacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.