Description

2-Bromo-2,2-Diphenylacetyl Chloride is a highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 2-bromo-2,2-diphenylacetyl moiety, a versatile functional group for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides with specific activity profiles.
• Peptide Mimetics & Modifications: Employed to incorporate bulky, lipophilic groups into peptide chains to alter bioavailability and receptor binding.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or mechanical properties.
• Academic & R&D Laboratories: Fundamental reagent for methodological development and exploring new organic reactions in research settings.

Basic Information

Product Name	2-Bromo-2,2-Diphenylacetyl Chloride
CAS No.	17397-37-4
Molecular Formula	C14H10BrClO
Molecular Weight	309.59 g/mol
Synonyms	α-Bromo-α-phenylbenzeneacetyl chloride; Diphenylbromoacetyl chloride; 2,2-Diphenyl-2-bromoacetyl chloride; (Bromodiphenylacetyl) chloride; Bromodiphenylacetyl chloride; NSC 404087; Benzeneacetic acid, α-bromo-α-phenyl-, chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,2-Diphenylacetyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.