Description

(3Ar,4Aα,9Aα)-Dodecahydro-6α-Hydroxy-8Aβ-Methyl-3,5-Bis(Methylene)Naphtho[2,3-B]Furan-2-One is a complex, high-purity sesquiterpene lactone derivative with a unique fused ring structure. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical candidates, offering a defined stereochemical framework for further chemical elaboration. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Organic Synthesis Research: Used in academic and industrial laboratories to study complex cyclization reactions and develop new synthetic methodologies.
• Natural Product Analog Development: Serves as a core scaffold for creating analogs of bioactive sesquiterpene lactones to explore new biological activities.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in chromatographic analysis.
• Material Science Precursor: Potential use in the development of specialized polymers or liquid crystals due to its rigid, polycyclic structure.

Basic Information

Product Name	(3Ar,4Aα,9Aα)-Dodecahydro-6α-Hydroxy-8Aβ-Methyl-3,5-Bis(Methylene)Naphtho[2,3-B]Furan-2-One
CAS No.	17322-82-6
Molecular Formula	C₁₆H₂₂O₃
Molecular Weight	262.34 g/mol
Synonyms	6α-Hydroxy-8aβ-methyldodecahydro-3,5-bis(methylene)naphtho[2,3-b]furan-2(3H)-one; Dodecahydro-6α-hydroxy-8aβ-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2-one; (3aR,4aS,9aS)-Dodecahydro-6α-hydroxy-8aβ-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2-one; 3,5-Bis(methylene)perhydronaphtho[2,3-b]furan-2-one derivative; NSC 338258; A sesquiterpene lactone intermediate.
EINECS	Contact for details

Quality Control

Our (3Ar,4Aα,9Aα)-Dodecahydro-6α-Hydroxy-8Aβ-Methyl-3,5-Bis(Methylene)Naphtho[2,3-B]Furan-2-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.