Description

2-Oxobutanoyl Chloride is a versatile and highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 2-oxobutanoyl moiety, enabling the construction of complex molecules for research and industrial applications. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing keto-acid functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require specific keto-acid chlorides for efficacy.
• Peptide & Protein Research: Employed as an acylating agent for modifying amino acids or for introducing protecting groups in peptide synthesis.
• Polymer Chemistry: Acts as a monomer or co-monomer in the production of specialized polyesters, polyamides, or other polymers with unique thermal or mechanical properties.
• Chemical Derivatization: Useful for preparing derivatives of alcohols, amines, and other nucleophiles for analytical purposes or to alter compound solubility.
• Material Science: Serves as a precursor for surface modification agents or for creating functionalized materials with specific surface properties.

Basic Information

Product Name	2-Oxobutanoyl Chloride
CAS No.	17118-74-0
Molecular Formula	C4H5ClO2
Molecular Weight	120.53 g/mol
Synonyms	2-Oxobutyryl Chloride; 3-Oxobutanoyl Chloride; α-Ketobutyryl Chloride; 2-Ketobutyryl Chloride; Butanoyl Chloride, 2-oxo-; 3-Oxobutyric Acid Chloride; Butyryl Chloride, 2-oxo-; 2-Oxobutanoic Acid Chloride
EINECS	241-185-6

Quality Control

Our 2-Oxobutanoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding synthetic applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and volatility. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Acid Impurities (Titration)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.