Description

2,4,5-Trichlorophenyl Chloroformate is a versatile and highly reactive chloroformate ester, serving as a critical intermediate in advanced organic synthesis. Its primary value lies in its ability to act as a protecting group or an activating agent for carboxylic acids, enabling the synthesis of complex molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the creation of amides, esters, and carbonates under controlled conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the trichlorophenyloxycarbonyl protecting group.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its trichlorophenyl moiety contributes to biological activity.
• Peptide Chemistry: Employed as a coupling reagent or for the preparation of activated esters in solid-phase and solution-phase peptide synthesis.
• Polymer Modification: Acts as a functionalizing agent to introduce reactive sites or cross-linking capabilities into polymer chains.
• Dye and Pigment Production: Intermediate in the synthesis of specialized dyes and colorants requiring the trichlorophenyl group for stability and hue.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating novel chemical entities in academic and industrial R&D labs.

Basic Information

Product Name	2,4,5-Trichlorophenyl Chloroformate
CAS No.	16947-69-6
Molecular Formula	C7H2Cl4O2
Molecular Weight	259.90 g/mol
Synonyms	2,4,5-Trichlorophenyl Carbonochloridate; Trichlorophenyl Chloroformate; Carbonochloridic Acid, 2,4,5-Trichlorophenyl Ester; (2,4,5-Trichlorophenoxy)carbonyl Chloride; TCPC; 2,4,5-Trichlorophenyloxycarbonyl Chloride
EINECS	Contact for details

Quality Control

Our 2,4,5-Trichlorophenyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and highly volatile; ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.