Description

2-Methoxyphenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key intermediate for introducing the 2-methoxyphenyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing methoxy-substituted aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that require specific aryl ether structures.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized phosphine or N-heterocyclic carbene ligands used in transition metal catalysis.
• Fine Chemical Manufacturing: Employed in the synthesis of dyes, pigments, and flavor & fragrance compounds.
• Material Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs, by building conjugated organic frameworks.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and for synthesizing novel compounds for biological screening.

Basic Information

Product Name	2-Methoxyphenylmagnesium Bromide
CAS No.	16750-63-3
Molecular Formula	C7H7BrMgO
Molecular Weight	211.34 g/mol
Synonyms	(2-Methoxyphenyl)magnesium Bromide; o-Methoxyphenylmagnesium Bromide; 1-Methoxy-2-magnesiobromobenzene; Magnesium, bromo(2-methoxyphenyl)-; Grignard Reagent, 2-Methoxyphenylmagnesium Bromide; 2-Methoxybenzene, bromomagnesio-; Bromo(2-methoxyphenyl)magnesium
EINECS	Contact for details

Quality Control

Our 2-Methoxyphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through comprehensive analytical testing, including titration for assay determination and GC/HPLC for purity and impurity profiling. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts violently with water and protic solvents. It must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a certified fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Clear brown to dark brown solution
Concentration (in specified solvent)	Typically 0.5 M - 2.0 M in THF or Diethyl Ether
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.