Description

Isopropylmagnesium Chloride is a highly reactive organometallic compound, widely recognized as a versatile Grignard reagent. Its primary value lies in its ability to act as a powerful nucleophile and strong base, facilitating critical carbon-carbon bond formation in complex organic syntheses. This makes it an indispensable tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors. The compound is typically supplied as a solution in common ethereal solvents like tetrahydrofuran or diethyl ether for ease of handling and reaction initiation.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing active pharmaceutical ingredients (APIs), particularly in the introduction of the isopropyl group and in nucleophilic addition reactions to carbonyl compounds.
• Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and insecticides where specific alkyl chains are required for bioactivity.
• Fine Chemical Production: Essential for synthesizing specialty chemicals, flavors, fragrances, and advanced organic compounds requiring precise molecular architecture.
• Polymer & Material Science: Serves as an initiator or modifying agent in the synthesis of specialized polymers and for surface functionalization of materials.
• Academic & Industrial R&D: A fundamental reagent in exploratory chemistry for developing new synthetic methodologies and novel molecular entities.

Basic Information

Product Name	Isopropylmagnesium Chloride
CAS No.	1068-55-9
Molecular Formula	C3H7ClMg
Molecular Weight	102.84 g/mol
Synonyms	i-PrMgCl; (Isopropyl)magnesium chloride; Magnesium, chloroisopropyl-; 2-Propylmagnesium chloride; Chloro(isopropyl)magnesium; Isopropyl magnesium chloride solution; Grignard reagent, isopropylmagnesium chloride
EINECS	213-946-8

Quality Control

Our Isopropylmagnesium Chloride solutions are manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm concentration (typically as a molar solution in THF or ether), active reagent content, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing assay results, titration data, and solvent specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile and easily oxidized (store under inert atmosphere) compound, it must be stored under a dry, inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat, sparks, and open flames. The solution is also sensitive to moisture and air. For specific temperature recommendations based on solvent and concentration, please consult the Safety Data Sheet.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Concentration	Typically 2.0 M in THF or Ether (Custom concentrations available)
Assay (Titration)	≥ 95% (as Isopropylmagnesium Chloride)
Identification (IR)	Conforms to structure
Solvent (GC)	Meets specified grade (THF, Diethyl ether, etc.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.