Description

sec-Butylmagnesium Chloride is a highly reactive organometallic compound widely used as a Grignard reagent in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile and strong base, facilitating the formation of carbon-carbon bonds essential for constructing complex molecular frameworks. This reagent is critical for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient alkylation or addition reactions.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the sec-butyl group into target molecules during the production of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and pesticides that incorporate sec-butyl moieties for enhanced efficacy.
• Fine Chemical Production: Employed in the preparation of specialty chemicals, flavors, fragrances, and advanced organic compounds.
• Polymer & Material Science: Serves as an initiator or modifying agent in the development of specialized polymers and functional materials.
• Academic & Industrial R&D: A fundamental tool in laboratory-scale organic synthesis for method development and exploratory chemistry.
• Nucleophilic Addition Reactions: Reacts with carbonyl compounds (aldehydes, ketones, esters) to form secondary and tertiary alcohols.

Basic Information

Product Name	sec-Butylmagnesium Chloride
CAS No.	15366-08-2
Molecular Formula	C4H9ClMg
Molecular Weight	116.87 g/mol
Synonyms	Butan-2-ylmagnesium chloride; (2-Butyl)magnesium chloride; Magnesium, chloro(1-methylpropyl)-; sec-BuMgCl; 2-Butylmagnesium chloride; 1-Methylpropylmagnesium chloride; Chloro(sec-butyl)magnesium; sec-C4H9MgCl
EINECS	Contact for details

Quality Control

Our sec-Butylmagnesium Chloride is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including titration for assay determination and gas chromatography (GC) for solvent and impurity profiling, to ensure consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing key parameters such as concentration in solution, free magnesium content, and acid titration value. Our quality systems support compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts violently with moisture and protic solvents. It must be stored under a dry, inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat, ignition sources, and incompatible materials such as acids, water, and alcohols. For solutions, typical recommended storage temperature is between 2°C and 8°C to maintain stability and reagent activity. Always handle using standard Schlenk line or glovebox techniques.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow liquid
Concentration (in THF/Diethyl ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR)	Conforms to structure
Acid Titration Value	Contact for details
Free Magnesium	≤ 2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.