Description

Nalmexone CAS NO 16676-27-0 is a synthetic opioid antagonist of significant pharmaceutical interest. This compound is valued for its specific receptor-binding profile, which makes it a crucial reference standard and research chemical in neuropharmacology. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in the study of opioid systems and drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control (QC/QA) in drug testing.
• Biomedical Research: Serves as a key pharmacological tool for in vitro and in vivo studies targeting opioid receptors, aiding in the understanding of addiction mechanisms and pain pathways.
• Metabolite Studies: Employed in the synthesis and identification of drug metabolites for pharmacokinetic and toxicological research.
• Analytical Chemistry: Acts as a critical component in calibrating instruments like HPLC, LC-MS, and GC-MS for accurate quantification in complex matrices.

Basic Information

Item	Detail
Product Name	Nalmexone
CAS No.	16676-27-0
Molecular Formula	C₂₂H₂₇NO₄
Molecular Weight	369.46 g/mol
Synonyms	Nalmexone; 5α-Nalmexone; EN-1620A; 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one; (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
EINECS	Contact for details

Quality Control

Our Nalmexone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced chromatographic and spectroscopic techniques. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.