Description

Retinylglucuronide is a water-soluble metabolite of vitamin A (retinol), formed through conjugation with glucuronic acid. This compound is significant for its role in the physiological transport and excretion of retinoids, offering enhanced stability and solubility compared to its parent compounds. It is primarily utilized in advanced pharmaceutical research and the development of cosmeceutical formulations targeting skin health and cellular regulation.

Application

• Pharmaceutical Intermediate: Key starting material or reference standard in the synthesis and research of novel retinoid-based therapeutics.
• Cosmeceutical Actives: Incorporated into anti-aging, skin-repair, and brightening serums and creams for its role in cellular communication and skin metabolism.
• Biochemical Research: Used as a critical reagent in studies of vitamin A metabolism, transport mechanisms, and detoxification pathways.
• Nutraceutical Development: Explored for formulating advanced dietary supplements with improved bioavailability of vitamin A derivatives.
• Cell Culture & Dermatology: Applied in in vitro models to study retinoid effects on cell differentiation and proliferation.
• Analytical Reference Standard: Serves as a high-purity standard for HPLC, LC-MS, and other analytical methods in quality control and metabolic studies.

Basic Information

Product Name	Retinylglucuronide
CAS No.	16639-19-3
Molecular Formula	C26H38O8
Molecular Weight	478.58 g/mol
Synonyms	Retinol glucuronide; Vitamin A glucuronide; all-trans-Retinyl β-D-glucuronide; Retinyl-β-glucuronide; RG; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-yl β-D-Glucopyranosiduronic Acid; Retinol D-glucuronide
EINECS	Contact for details

Quality Control

Our Retinylglucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, keep the product desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.