Description

(R)-2,3,5,6-Tetrahydro-6-Phenylimidazo[2,1-B]Thiazole Monohydrochloride is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it provides a critical, enantiomerically pure building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific stereochemistry. Pharmaceutical R&D teams and fine chemical manufacturers need this material for the production of sophisticated drug candidates, where its defined configuration is essential for biological activity and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients, particularly those targeting the central nervous system.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in studies exploring new catalytic methodologies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with optimized efficacy.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	(R)-2,3,5,6-Tetrahydro-6-Phenylimidazo[2,1-B]Thiazole Monohydrochloride
CAS No.	16595-76-9
Molecular Formula	C11H13N2S • HCl
Molecular Weight	240.76 g/mol
Synonyms	(R)-Levamisole Hydrochloride; (R)-(-)-Tetramisole Hydrochloride; (R)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride; (R)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride; (R)-L-Tetramisole HCl; (R)-L-(-)-Tetramisole HCl; (R)-Enantiomer of Tetramisole Hydrochloride; (R)-Imidazo[2,1-b]thiazole derivative
EINECS	Contact for details

Quality Control

Our (R)-2,3,5,6-Tetrahydro-6-Phenylimidazo[2,1-B]Thiazole Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.