Description

2,5-Piperazinedione,3-[(Aminooxy)Methyl]-6-Methyl-,(3R-Cis)-(9Ci) is a specialized heterocyclic compound featuring a piperazinedione core with an aminooxymethyl substituent. This molecule is of significant interest as a key chiral building block and advanced pharmaceutical intermediate in synthetic organic chemistry. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel therapeutic agents, particularly in the fields of oncology and infectious diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereochemical complexity into target molecules for medicinal chemistry programs.
• Bioconjugation Research: The aminooxy functional group enables its use in chemoselective ligation strategies for labeling proteins, antibodies, or other biomolecules.
• Chemical Biology Probes: Employed in the development of activity-based probes and inhibitors for studying biological processes at a molecular level.
• Peptidomimetic Design: Acts as a constrained scaffold in the design of peptidomimetics to enhance metabolic stability and bioavailability.
• Academic & Contract Research: Essential for fundamental research in synthetic methodology and new reaction development within university and CRO laboratories.

Basic Information

Product Name	2,5-Piperazinedione,3-[(Aminooxy)Methyl]-6-Methyl-,(3R-Cis)-(9Ci)
CAS No.	16562-03-1
Molecular Formula	C7H11N3O3
Molecular Weight	185.18 g/mol
Synonyms	(3R,6S)-3-(Aminooxymethyl)-6-methylpiperazine-2,5-dione; 3-(Aminooxymethyl)-6-methyl-2,5-piperazinedione; (3R-cis)-3-[(Aminooxy)methyl]-6-methyl-2,5-piperazinedione; (3R,6S)-3-(Hydroxyamino)methyl-6-methyl-2,5-diketopiperazine; Aminooxy-methyl-Diketopiperazine derivative; Chiral Diketopiperazine building block; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our high-purity 2,5-Piperazinedione derivative is manufactured under controlled conditions to ensure batch-to-batch consistency and reliability for sensitive research applications. All materials undergo rigorous analytical testing, including chiral purity verification and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific tests is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.