Description

2,5-Piperazinedione,3-[(Aminooxy)Methyl]-6-Methyl-,Stereoisomer(8Ci) CAS NO 16561-99-2 is a specialized heterocyclic compound featuring a piperazinedione core modified with an aminooxymethyl functional group. This unique structure makes it a valuable building block and intermediate in advanced synthetic chemistry, particularly for the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and the synthesis of complex organic targets.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a constrained scaffold or precursor for creating libraries of compounds in drug discovery programs, leveraging its piperazine-2,5-dione core.
• Peptidomimetic Synthesis: Acts as a building block for designing and synthesizing peptidomimetics, which are molecules that mimic the structure and function of peptides.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function or protein-protein interactions due to its reactive aminooxy group.
• Asymmetric Synthesis: Employed in stereoselective synthesis processes to introduce chiral centers into complex molecular architectures.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate R&D labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2,5-Piperazinedione,3-[(Aminooxy)Methyl]-6-Methyl-,Stereoisomer(8Ci)
CAS No.	16561-99-2
Molecular Formula	C7H11N3O3
Molecular Weight	185.18 g/mol
Synonyms	3-(Aminooxymethyl)-6-methylpiperazine-2,5-dione; (3S)-3-[(Aminooxy)methyl]-6-methyl-2,5-piperazinedione; 3-(Aminooxymethyl)-6-methyl-2,5-piperazinedione; 6-Methyl-3-(aminooxymethyl)piperazine-2,5-dione; (S)-3-(Aminooxymethyl)-6-methylpiperazine-2,5-dione; 3-(Hydroxyamino)methyl-6-methyl-2,5-diketopiperazine; A building block for DKPs.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity, critical for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.