Description

Brevilin A CAS NO 16503-32-5 is a bioactive sesquiterpene lactone compound of significant interest in pharmaceutical and biochemical research. Its unique chemical structure makes it a valuable reference standard and a key intermediate for the development of novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and natural product chemistry sectors who require reliable, well-characterized materials for their critical work.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished pharmaceutical products in quality control laboratories.
• Bioactivity Research: Serves as a key investigational compound in pharmacological studies targeting inflammation, cancer, and microbial infections due to its sesquiterpene lactone core.
• Natural Product Isolation & Synthesis: Acts as a critical intermediate or target molecule in the semi-synthesis and total synthesis of complex natural products.
• Analytical Method Development: Employed as a certified reference material (CRM) to develop and validate analytical methods such as HPLC, LC-MS, and NMR for complex matrices.
• Biochemical Pathway Studies: Utilized in cell-based assays to study specific signaling pathways and mechanisms of action.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	Brevilin A
CAS No.	16503-32-5
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	Brevilin A; 8-Angeloyloxy-4,5-epoxy-1(10)-germacren-6,12-olide; (1aR,4E,7aS,10aS,10bS)-1a,2,3,6,7,7a,8,10a-Octahydro-1a,5-dimethyl-8-methylene-4,10-dioxooxireno[9,10]cyclodeca[1,2-b]furan-9-yl (2Z)-2-methyl-2-butenoate; 4,5-Epoxy-1(10),11(13)-germacradien-12,8-olide, 8-angeloyloxy-; A 26771B; NSC 339588
EINECS	Contact for details

Quality Control

Every batch of Brevilin A is produced and analyzed under strict quality management protocols. Our products undergo rigorous identity confirmation, purity assessment, and impurity profiling using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.