Description

5-(2-Pyrazinyl)-1H-Tetrazole is a heterocyclic organic compound featuring a tetrazole ring fused with a pyrazine moiety, serving as a versatile and valuable synthetic building block. This compound is particularly significant for its role as a key intermediate in the synthesis of complex molecules, especially within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing tetrazole bioisosteres for improved metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the tetrazole ring can enhance biological activity.
• Coordination Chemistry & Material Science: Acts as a polydentate ligand for constructing metal-organic frameworks (MOFs) and coordination polymers with potential applications in catalysis, gas storage, and sensing.
• Energetic Materials Research: Investigated as a component in the development of high-nitrogen-content compounds and propellant formulations due to its nitrogen-rich structure.
• Chemical Biology & Bioconjugation: Serves as a reactive handle for click chemistry and other bioorthogonal reactions to label biomolecules or create chemical probes.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to impart specific thermal or chemical properties to specialty polymers.

Basic Information

Product Name	5-(2-Pyrazinyl)-1H-Tetrazole
CAS No.	16289-54-6
Molecular Formula	C5H4N6
Molecular Weight	148.13 g/mol
Synonyms	5-(Pyrazin-2-yl)-1H-tetrazole; 5-(2-Pyrazinyl)-1H-tetrazole; 2-(1H-Tetrazol-5-yl)pyrazine; 5-(2-Pyrazinyl)tetrazole; 1H-Tetrazole, 5-(2-pyrazinyl)-; Pyrazine-2-carbonitrile, azido- (precursor); 2-Tetrazolylpyrazine
EINECS	Contact for details

Quality Control

Our 5-(2-Pyrazinyl)-1H-Tetrazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.