Description

3-Keto-7α,12α-Dihydroxy-5α-Cholanic Acid is a key intermediate in the synthesis of bile acids and related steroid compounds. Its precise structure makes it a critical building block for pharmaceutical research and fine chemical manufacturing. This high-purity intermediate is essential for laboratories and production facilities developing active pharmaceutical ingredients (APIs), reference standards, and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of ursodeoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and substrate in metabolic pathway studies, enzyme inhibition assays, and hepatology research.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the production of complex steroid derivatives and labeled compounds.
• API Development: Employed in the research and development of new drug candidates targeting liver and metabolic disorders.
• Diagnostic Reagents: Utilized in the formulation of calibrators and controls for clinical diagnostic tests related to liver function.

Basic Information

Product Name	3-Keto-7α,12α-Dihydroxy-5α-Cholanic Acid
CAS No.	16265-24-0
Molecular Formula	C₂₄H₃₈O₅
Molecular Weight	406.56 g/mol
Synonyms	7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic Acid; 3-Oxo-7α,12α-dihydroxy-5β-cholanic Acid; 3-Ketochenodeoxycholic Acid; 3-Oxochenodeoxycholic Acid; 7α,12α-Dihydroxy-3-oxocholanic Acid; 3-Dehydrochenodeoxycholic Acid
EINECS	Contact for details

Quality Control

Our 3-Keto-7α,12α-Dihydroxy-5α-Cholanic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.