Description

Cyclobutanecarbonyl Chloride, 3-Chloro-3-Methyl- (8Ci) is a highly reactive and versatile organic acid chloride derivative of cyclobutane. This compound matters as a critical building block in advanced organic synthesis, enabling the efficient introduction of the cyclobutylcarbonyl moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting cyclobutane-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclobutane ring can confer specific biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and high-performance materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation, esterification, and amide bond formation reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic complexes for catalytic applications.
• Chemical Biology Probe Synthesis: Facilitates the creation of chemical probes for studying biological pathways and protein functions.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3-Chloro-3-Methyl- (8Ci)
CAS No.	16200-72-9
Molecular Formula	C6H8Cl2O
Molecular Weight	167.03 g/mol
Synonyms	3-Chloro-3-methylcyclobutanecarbonyl chloride; 3-Methyl-3-chlorocyclobutanecarboxylic acid chloride; 3-Chloro-3-methylcyclobutane-1-carbonyl chloride; 1-(Chlorocarbonyl)-3-chloro-3-methylcyclobutane; Cyclobutanecarbonyl chloride, 3-chloro-3-methyl-; 3-Chloro-3-methyl-1-cyclobutanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3-Chloro-3-Methyl- (8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or HPLC and impurity profiling, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.