Description

Diethyl Cromoglycate is a synthetic organic compound belonging to the chromone class, recognized for its role as a key intermediate in pharmaceutical synthesis. Its primary commercial value lies in its structural relationship to cromoglicic acid (cromolyn), a well-established mast cell stabilizer used in anti-allergic and anti-asthmatic medications. This makes it a critical building block for research and development laboratories and fine chemical manufacturers focused on respiratory therapeutics. Industries involved in the production of active pharmaceutical ingredients (APIs) and specialty fine chemicals are the principal users of this material.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of cromoglicic acid (cromolyn sodium) and related analogs for anti-allergy medications.
• Research & Development: Used in medicinal chemistry research to develop new mast cell stabilizers and investigate mechanisms of allergic response.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex chromone-based molecules with potential biological activity.
• Reference Standard: Can be utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Diethyl Cromoglycate
CAS No.	16150-45-1
Molecular Formula	C15H16O7
Molecular Weight	308.28 g/mol
Synonyms	Diethyl 5,5'-[(2-Hydroxytrimethylene)dioxy]bis(4-oxo-4H-1-benzopyran-2-carboxylate); Diethyl 1,3-Bis(2-carboxy-4-oxochromen-5-yloxy)-2-hydroxypropane; Cromolyn Diethyl Ester; Diethyl Cromoglycate; FPL 670; INTAL Intermediate; Diethyl Cromoglicate
EINECS	240-288-7

Quality Control

Our Diethyl Cromoglycate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets the high-purity standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as purity (by HPLC), residual solvents, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.