Description

4-[4-(3-Methoxyphenyl)-1-Piperazinyl]-3-Pyridinamine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperazinyl-pyridinamine structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and life sciences sectors engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Research & Development: Serves as a scaffold for medicinal chemistry research, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the controlled synthesis of complex APIs that require the specific 3-methoxyphenyl-piperazine moiety.
• Biochemical Research: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	4-[4-(3-Methoxyphenyl)-1-Piperazinyl]-3-Pyridinamine
CAS No.	16122-19-3
Molecular Formula	C16H20N4O
Molecular Weight	284.36 g/mol
Synonyms	3-Amino-4-[4-(3-methoxyphenyl)piperazin-1-yl]pyridine; 3-Pyridinamine, 4-[4-(3-methoxyphenyl)-1-piperazinyl]-; 4-(4-(3-Methoxyphenyl)piperazin-1-yl)pyridin-3-amine; 1-(3-Methoxyphenyl)-4-(3-amino-4-pyridyl)piperazine; 16122-19-3
EINECS	Contact for details

Quality Control

Our 4-[4-(3-Methoxyphenyl)-1-Piperazinyl]-3-Pyridinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via FT-IR and NMR, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.