Description

(R)-(-)-3-Methylpiperidine CAS NO 16078-25-4 is a high-purity chiral piperidine derivative, a crucial building block in asymmetric synthesis. Its enantiomeric purity makes it an indispensable intermediate for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel, stereoselective compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various APIs, including central nervous system (CNS) agents, analgesics, and antiviral drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and insecticides for enhanced efficacy and environmental safety.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in asymmetric hydrogenation and other stereoselective transformations.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and developing novel chiral molecules.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific chiral aroma chemicals.

Basic Information

Product Name	(R)-(-)-3-Methylpiperidine
CAS No.	16078-25-4
Molecular Formula	C6H13N
Molecular Weight	99.17 g/mol
Synonyms	(R)-3-Methylpiperidine; (R)-(-)-3-Methylpiperidine; (R)-3-Methylpiperidine; (R)-3-Pipecoline; (3R)-Methylpiperidine; (-)-3-Methylpiperidine; (R)-3-Methylhexahydropyridine; UNII-9Q0L8QYV8H
EINECS	240-224-6

Quality Control

Our (R)-(-)-3-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by GC or HPLC, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Specific Rotation ([α]D20)	-15° to -20° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.