Description

Boron Trifluoride-Methanol CAS NO 16045-88-8 is a specialized chemical complex formed from boron trifluoride and methanol, serving as a powerful Lewis acid catalyst and reagent. This compound is valued for its ability to facilitate complex organic transformations, particularly in methylation and esterification reactions, under mild conditions. It is an essential tool for research and development laboratories, pharmaceutical synthesis, and fine chemical manufacturing where precise catalysis is required.

Application

• Catalyst in Organic Synthesis: Acts as a potent Lewis acid catalyst for Friedel-Crafts alkylations, acylations, and other electrophilic aromatic substitution reactions.
• Methylating Agent: Used for the selective methylation of alcohols, phenols, carboxylic acids, and amines in pharmaceutical intermediate synthesis.
• Esterification Promoter: Facilitates the esterification of carboxylic acids, including the preparation of methyl esters for gas chromatography (GC) analysis.
• Polymerization Initiator: Employed as a co-catalyst or initiator in the polymerization of olefins and other monomers.
• Laboratory Reagent: A key reagent for complex molecule construction in academic and industrial R&D settings for novel compound libraries.
• Fine Chemical Production: Used in the multi-step synthesis of agrochemicals, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	Boron Trifluoride-Methanol
CAS No.	16045-88-8
Molecular Formula	CH3BF3O (commonly represented as BF3·CH3OH)
Molecular Weight	99.85 g/mol
Synonyms	Boron Trifluoride Methanol Complex; BF3-Methanol; BF3-Methanol Adduct; Methanol, compd. with boron trifluoride (1:1); Trifluoroborane-Methanol; Boron Fluoride-Methanol; Methyl Alcohol-Boron Trifluoride Complex; Borane, trifluoro-, compd. with methanol (1:1)
EINECS	240-170-6

Quality Control

Our Boron Trifluoride-Methanol complex is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical R&D and industrial catalysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its nature as a strong acid/organic solvent and highly volatile compound, containers must be kept tightly sealed and upright to prevent moisture ingress and pressure buildup. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (BF3 Content)	≥ 47.0 %
Methanol Content	Balance
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.