Description

1-(4-Chloro-Benzenesulfonyl)-Piperazine is a versatile sulfonamide-based piperazine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, providing both a reactive sulfonyl chloride precursor and a piperazine moiety for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel drug candidates, particularly in central nervous system (CNS) and antimicrobial therapeutic areas.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with tailored biological activity.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and synthesizing complex heterocyclic compounds in academic and industrial R&D labs.
• Material Science: Used in the synthesis of specialty polymers and functional materials requiring sulfonamide linkages.
• Ligand & Catalyst Development: Serves as a precursor for creating novel ligands used in catalytic processes and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(4-Chloro-Benzenesulfonyl)-Piperazine
CAS No.	16017-53-1
Molecular Formula	C10H13ClN2O2S
Molecular Weight	260.74 g/mol
Synonyms	4-Chloro-N-piperazin-1-ylbenzenesulfonamide; 1-(4-Chlorophenylsulfonyl)piperazine; 4-Chlorobenzenesulfonylpiperazine; N-(4-Chlorophenylsulfonyl)piperazine; Piperazine, 1-(p-chlorobenzenesulfonyl)-; p-Chlorobenzenesulfonylpiperazine; 4-Chloro-N-(piperazin-1-yl)benzenesulfonamide; 1-(4-Chlorobenzene-1-sulfonyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Benzenesulfonyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.