Description

3-Amino-5-(Trifluoromethyl)-2-Pyrazinecarboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its pyrazine core, amino group, and trifluoromethyl substituent. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its unique trifluoromethylated pyrazine scaffold.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, electron-deficient aromatic structure.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyrazine derivatives.

Basic Information

Product Name	3-Amino-5-(Trifluoromethyl)-2-Pyrazinecarboxylic Acid
CAS No.	16014-65-6
Molecular Formula	C6H4F3N3O2
Molecular Weight	207.11 g/mol
Synonyms	3-Amino-5-(trifluoromethyl)pyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 3-amino-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-3-aminopyrazine-2-carboxylic acid; 3-Amino-5-trifluoromethylpyrazine-2-carboxylic acid; 3-Amino-5-trifluoromethyl-2-pyrazinecarboxylic acid; 16014-65-6; ATFPC
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(Trifluoromethyl)-2-Pyrazinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.