Description

2,5-Piperazinedione,3,6-Bis(Hydroxymethyl)-,cis-(8Ci,9Ci) is a high-purity, functionalized diketopiperazine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic scaffolds found in potential drug candidates.
• Peptidomimetic Research: Used to create conformationally constrained peptide analogs to enhance metabolic stability and bioavailability.
• Ligand Synthesis: Employed in the preparation of chelating agents and ligands for catalysis or metal coordination chemistry.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing novel polyamides or functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Academic & Industrial R&D: Serves as a critical starting material for exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	2,5-Piperazinedione,3,6-Bis(Hydroxymethyl)-,cis-(8Ci,9Ci)
CAS No.	15996-17-5
Molecular Formula	C8H12N2O4
Molecular Weight	200.19 g/mol
Synonyms	cis-3,6-Bis(hydroxymethyl)-2,5-piperazinedione; cis-3,6-Bis(hydroxymethyl)-2,5-diketopiperazine; 3,6-Bis(hydroxymethyl)-2,5-piperazinedione; 2,5-Diketopiperazine-3,6-dimethanol; (3S,6S)-3,6-Bis(hydroxymethyl)piperazine-2,5-dione; (3R,6R)-3,6-Bis(hydroxymethyl)piperazine-2,5-dione; cis-BHMP; Diketopiperazine dimethanol derivative
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3,6-Bis(Hydroxymethyl)-,cis-(8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.