Description

Tms Dl-Valine CAS NO 15984-93-7 is a protected derivative of the amino acid valine, where the trimethylsilyl (TMS) group serves as a key protecting group for the amino functionality. This compound is of significant value in advanced organic synthesis, particularly in peptide chemistry and pharmaceutical research, where it enables precise control over reaction pathways. It is primarily needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the synthesis of complex peptides, bioactive molecules, and novel drug candidates.

Application

• Peptide Synthesis: As a protected amino acid building block for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Pharmaceutical Intermediates: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Biochemical Research: Used in studies involving amino acid metabolism, enzyme substrates, and the development of biochemical probes.
• Asymmetric Synthesis: Employed in chiral synthesis and resolution processes due to its racemic (DL) form, allowing access to both enantiomers.
• Protecting Group Chemistry: Serves as a model compound for studying trimethylsilyl protection/deprotection strategies in synthetic methodology.
• Reference Standard: Utilized as an analytical standard in chromatography (HPLC, GC) for quality control and method development in related chemical processes.

Basic Information

Product Name	Tms Dl-Valine
CAS No.	15984-93-7
Molecular Formula	C8H19NO2Si
Molecular Weight	189.33 g/mol
Synonyms	N-(Trimethylsilyl)-DL-valine; DL-Valine, N-(trimethylsilyl)-; Trimethylsilyl-DL-valine; N-TMS-DL-valine; Valine, N-(trimethylsilyl)-, DL-; 2-((Trimethylsilyl)amino)-3-methylbutanoic acid; TMS-Val-OH (DL); N-Trimethylsilylvaline (racemic)
EINECS	Contact for details

Quality Control

Our Tms Dl-Valine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopy (IR, NMR), to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent loss and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.