Description

4-Methyl Phenoxy Acetyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-methylphenoxyacetyl moiety, a key structural component in the development of active pharmaceutical ingredients and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring phenoxyacetyl functional groups.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators where the 4-methylphenoxy moiety contributes to biological efficacy.
• Peptide Chemistry: Employed as an acylating agent for the protection of amino groups or the synthesis of peptide analogs.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polymers and liquid crystal materials.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Methyl Phenoxy Acetyl Chloride
CAS No.	15516-47-9
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	p-Methylphenoxyacetyl Chloride; 4-Methylphenoxyacetyl Chloride; (4-Methylphenoxy)acetyl Chloride; 2-(4-Methylphenoxy)acetyl Chloride; Acetyl chloride, 2-(4-methylphenoxy)-; p-Cresoxyacetyl Chloride; 4-Methylphenoxyethanoyl Chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl Phenoxy Acetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis to meet specific pharmacopeial (e.g., USP, EP) or internal specifications for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, alcohols, and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.