Description

11-Hydroxy-8,12,14-Eicosatrienoic Acid is a specialized hydroxy fatty acid derivative of arachidonic acid, serving as a key intermediate in the study of eicosanoid biosynthesis and lipid signaling pathways. Its value lies in its role as a biochemical tool for researching inflammation, cell signaling, and metabolic regulation. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors who require high-purity reference standards and synthetic intermediates.

Application

• Biochemical Research Standard: Used as a high-purity reference material in lipidomics and eicosanoid research.
• Pharmaceutical Intermediate: Serves as a critical synthetic building block for developing novel anti-inflammatory and metabolic disorder therapeutics.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the mechanisms of hydroxy fatty acids in cellular communication and inflammation pathways.
• Enzyme Substrate: Acts as a substrate for studying the activity and inhibition of lipoxygenase (LOX) and cytochrome P450 enzymes.
• Metabolite Analysis: Used in the development and validation of analytical methods (LC-MS, GC-MS) for detecting and quantifying lipid metabolites.
• Academic & Institutional Research: Supports fundamental research in universities and government labs focused on lipid biochemistry and pharmacology.

Basic Information

Product Name	11-Hydroxy-8,12,14-Eicosatrienoic Acid
CAS No.	15514-86-0
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	11-HETE; 11-Hydroxyeicosatetraenoic Acid; 11(S)-HETE; 11-Hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic Acid; 11-Hydroxyarachidonic Acid; 11(S)-Hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic Acid; (±)11-HETE; 11-Hydroxy-8,12,14-icosatrienoic Acid
EINECS	Contact for details

Quality Control

Our 11-Hydroxy-8,12,14-Eicosatrienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Isomeric Purity	Specification available upon request
Solubility	Soluble in ethanol, DMSO, dimethyl formamide

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.