Description

15-Hydroxy-8,11,13-eicosatrienoic acid is a specialized hydroxy fatty acid derivative of eicosatrienoic acid, serving as a key intermediate in the study of lipid mediators and eicosanoid biosynthesis pathways. This compound is valued for its role as a biochemical tool in research focused on inflammation, cell signaling, and metabolic processes. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for analytical standards, reference materials, and investigative studies.

Application

• Biochemical Research: Used as a reference standard and intermediate in the study of lipoxygenase and cytochrome P450 pathways.
• Pharmaceutical Development: Investigated as a potential precursor or analog in the development of novel anti-inflammatory or pro-resolving lipid mediators.
• Cell Signaling Studies: Employed to explore its effects on cellular receptors and signaling cascades related to immune response and metabolism.
• Analytical Chemistry: Serves as a high-purity standard for method development and validation in chromatographic (HPLC, GC) and mass spectrometric analyses.
• Metabolomics & Lipidomics: A critical component in profiling and quantifying oxylipins and other oxidized lipid species in biological samples.
• Enzymology: Used as a substrate to study the activity and specificity of enzymes involved in fatty acid hydroxylation and oxidation.

Basic Information

Product Name	15-Hydroxy-8,11,13-eicosatrienoic Acid
CAS No.	15384-21-1
Molecular Formula	C₂₀H₃₄O₃
Molecular Weight	322.48 g/mol
Synonyms	15-HETE; 15-Hydroxyeicosatrienoic Acid; 15(S)-HETE; 15-Hydroxy-8,11,13-eicosatrienoate; (15S)-15-Hydroxyicosa-8,11,13-trienoic acid; 15-Hydroxy-8,11,13-all-cis-eicosatrienoic Acid; 15-Lipoxygenase metabolite; 15-Hydroxy-5,8,11,13-eicosatetraenoic Acid (common misnomer, verify structure)
EINECS	Contact for details

Quality Control

Our 15-Hydroxy-8,11,13-eicosatrienoic acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (by GC)	≥ 90%
Solubility	Soluble in ethanol, DMSO, and organic solvents
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.