Description

1,2,5-Oxadiazole-3-Carbonyl Chloride, 4-Methyl- (9Ci) is a highly reactive and versatile chemical building block, specifically a functionalized furoxan derivative. Its value lies in its role as a key acylating agent for introducing the 4-methyl-1,2,5-oxadiazole-3-carbonyl moiety into target molecules, enabling the synthesis of novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly in medicinal chemistry for creating potential drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in the development of heterocyclic compounds for various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the oxadiazole ring can contribute to biological activity.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands, or functional materials with unique electronic or structural properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Energetic Materials Research: Investigated as a potential intermediate in the development of novel high-energy-density materials (HEDMs) due to the furoxan structure.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical and custom synthesis houses serving the R&D needs of global clients.

Basic Information

Item	Detail
Product Name	1,2,5-Oxadiazole-3-Carbonyl Chloride, 4-Methyl- (9Ci)
CAS No.	15323-68-9
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	4-Methyl-1,2,5-oxadiazole-3-carbonyl chloride; 4-Methyl-furoxan-3-carbonyl chloride; 3-Chlorocarbonyl-4-methyl-1,2,5-oxadiazole; 4-Methyl-[1,2,5]oxadiazole-3-carbonyl chloride; 4-Methylfuroxan-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1,2,5-Oxadiazole-3-Carbonyl Chloride, 4-Methyl- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We support cGMP compliance for advanced applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.