Description

3-(4-Methyl-Piperazin-1-Yl)-3-Oxo-Propionitrile is a versatile and high-value chemical intermediate characterized by its reactive nitrile and amide functionalities. This compound is crucial for the synthesis of complex molecules, particularly in the pharmaceutical sector, where it serves as a key building block for active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its structural motif for biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale operations.
• Bioconjugation & Probe Development: Utilized in biochemical research for creating labeled probes and conjugates due to its reactive sites suitable for linking to biomolecules.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialized polymers with unique properties.

Basic Information

Product Name	3-(4-Methyl-Piperazin-1-Yl)-3-Oxo-Propionitrile
CAS No.	15029-34-2
Molecular Formula	C8H13N3O
Molecular Weight	167.21 g/mol
Synonyms	3-Oxo-3-(4-methyl-1-piperazinyl)propanenitrile; 3-(4-Methylpiperazin-1-yl)-3-oxopropanenitrile; 4-Methyl-1-piperazinepropanenitrile, 3-oxo-; 3-(N-Methylpiperazino)propionitrile; Propanenitrile, 3-oxo-3-(4-methyl-1-piperazinyl)-; 15029-34-2; 3-(4-Methylpiperazine-1-carbonyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-(4-Methyl-Piperazin-1-Yl)-3-Oxo-Propionitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.