Description

3-Oxo-3-(4-Phenyl-Piperazin-1-Yl)-Propionitrile is a high-purity, versatile chemical intermediate featuring a piperazine core linked to a cyanoacetophenone moiety. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering a unique structural handle for further functionalization. Pharmaceutical R&D and fine chemical manufacturers need it for developing new therapeutic agents, particularly in central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Organic Synthesis Building Block: Serves as a versatile synthon for constructing complex heterocyclic compounds in academic and industrial research.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying enzyme and receptor function.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with specific electronic or binding properties.

Basic Information

Product Name	3-Oxo-3-(4-Phenyl-Piperazin-1-Yl)-Propionitrile
CAS No.	14761-40-1
Molecular Formula	C13H15N3O
Molecular Weight	229.28 g/mol
Synonyms	3-(4-Phenylpiperazin-1-yl)-3-oxopropanenitrile; 1-(2-Cyanoacetyl)-4-phenylpiperazine; 4-Phenyl-1-(2-cyanoacetyl)piperazine; 2-Cyano-1-(4-phenyl-1-piperazinyl)ethanone; 3-Oxo-3-(4-phenyl-1-piperazinyl)propanenitrile; 3-(4-Phenyl-1-piperazinyl)-3-oxopropanenitrile; N-(4-Phenylpiperazin-1-yl)cyanoacetamide
EINECS	Contact for details

Quality Control

Our 3-Oxo-3-(4-Phenyl-Piperazin-1-Yl)-Propionitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.