Description

6-Iodohexanoyl Chloride is a versatile bifunctional organic intermediate featuring both a reactive acid chloride group and an iodoalkyl chain. This compound is crucial for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science, where it serves as a key building block for introducing functionalized hexyl linkers. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs), ligands, and polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a functionalized alkyl chain for conjugation or as a spacer.
• Bioconjugation & Probe Synthesis: Used to attach fluorophores, biotin, or other reporter molecules to biomolecules (proteins, peptides) via the reactive acid chloride group, with the iodo group available for further modification.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating functional polymers, dendrimers, and advanced materials with specific chemical handles.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators that incorporate halogenated alkyl motifs.
• Ligand & Catalyst Development: Used to synthesize chelating ligands for metal catalysts or as a precursor for organometallic compounds in catalysis.
• Chemical Biology Tool Development: Employed in creating activity-based probes (ABPs) and other chemical tools for studying enzyme function and cellular processes.

Basic Information

Product Name	6-Iodohexanoyl Chloride
CAS No.	14500-34-6
Molecular Formula	C6H10ClIO
Molecular Weight	260.50 g/mol
Synonyms	6-Iodocaproyl Chloride; Iodohexanoyl Chloride; Hexanoyl Chloride, 6-iodo-; ω-Iodohexanoyl Chloride; 6-Iodo-n-caproyl Chloride; 5-Iodopentanecarbonyl Chloride; 6-Iodo-1-oxohexan-1-yl Chloride
EINECS	Contact for details

Quality Control

Our 6-Iodohexanoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.