Description

Iso Methadone CAS NO 14474-54-5 is a synthetic opioid compound of significant interest in pharmaceutical research and development. This chemical serves as a key intermediate or reference standard in the synthesis and analytical profiling of opioid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers focused on neuropharmacology, analgesic development, and forensic analysis. Our supply ensures high purity and batch-to-batch consistency, which is critical for reliable research outcomes and regulatory compliance.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex opioid analgesic compounds and their derivatives for research purposes.
• Analytical Reference Standard: Used as a certified reference material (CRM) in high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS) for method development, validation, and quality control testing.
• Pharmacological Research: Employed in in vitro and in vivo studies to investigate opioid receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Forensic Science: Acts as a standard for the identification and quantification of opioid substances in forensic toxicology laboratories.
• Chemical Synthesis Studies: Utilized in academic and industrial research to explore novel synthetic routes and catalytic processes for heterocyclic and pharmaceutical chemistry.

Basic Information

Product Name	Iso Methadone
CAS No.	14474-54-5
Molecular Formula	C21H27NO
Molecular Weight	309.45 g/mol
Synonyms	Isomethadone; (+)-Isomethadone; d-Isomethadone; (R)-Isomethadone; 6-Dimethylamino-4,4-diphenyl-3-heptanone; NSC 1026; LAAM Impurity A (related compound)
EINECS	Contact for details

Quality Control

Every batch of Iso Methadone is produced and tested under a strict quality management system. We provide comprehensive analytical data to support its use in research and development. Specifications typically include identity confirmation by spectroscopic methods, purity assay by chromatographic techniques, and control of related substances. Certificates of Analysis (COA) detailing batch-specific results are available upon request, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.