Description

Cyclopropyltriphenylphosphonium Bromide is a versatile organophosphorus salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stable ylide precursor for the synthesis of cyclopropyl-containing compounds via Wittig and related olefination reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs) containing cyclopropane rings, which are valuable motifs in drug discovery for metabolic stability.
• Agrochemical Synthesis: Used in the production of pesticides and herbicides where the cyclopropyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a building block for creating novel organic frameworks and functionalized polymers with specific electronic or structural properties.
• Wittig Reaction Reagent: Acts as a specialized phosphonium ylide precursor for the formation of methylenecyclopropane derivatives and other strained olefins.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and the synthesis of complex natural product analogs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring cyclopropanation.

Basic Information

Item	Details
Product Name	Cyclopropyltriphenylphosphonium Bromide
CAS No.	14114-05-7
Molecular Formula	C21H20BrP
Molecular Weight	383.26 g/mol
Synonyms	Triphenyl(cyclopropyl)phosphonium Bromide; Cyclopropyltriphenylphosphonium Bromide; (Cyclopropylmethyl)triphenylphosphonium Bromide; Phosphonium, triphenylcyclopropyl-, bromide; Cyclopropylmethyltriphenylphosphonium Bromide; Cyclopropyl(triphenyl)phosphonium Bromide; CPTPB
EINECS	Contact for details

Quality Control

Our Cyclopropyltriphenylphosphonium Bromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.