Description

[1,1'-Biphenyl]-2-Carbonyl Chloride is a specialized aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity as an acylating agent, enabling the efficient introduction of the biphenyl-2-carbonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs) containing a biphenyl scaffold.
• Agrochemical Synthesis: Used in the production of herbicides and fungicides where the biphenyl structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or modifying agent for synthesizing high-performance polymers and liquid crystalline materials.
• Dyestuff and Pigment Manufacturing: Intermediate in the production of complex organic dyes and pigments requiring the biphenyl group for color and stability.
• Organic Synthesis & Research: A versatile reagent for peptide coupling, Friedel-Crafts acylation, and the preparation of ketones, esters, and amides in academic and industrial R&D.

Basic Information

Product Name	[1,1'-Biphenyl]-2-Carbonyl Chloride
CAS No.	14002-52-9
Molecular Formula	C13H9ClO
Molecular Weight	216.66 g/mol
Synonyms	2-Biphenylcarbonyl Chloride; 2-Phenylbenzoyl Chloride; o-Phenylbenzoyl Chloride; Biphenyl-2-carbonyl chloride; (1,1'-Biphenyl)-2-carbonyl chloride; 2-Carboxybiphenyl Chloride; NSC 403107; 2-Benzoylphenyl Chloride
EINECS	237-804-9

Quality Control

Our [1,1'-Biphenyl]-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and ensure maximum shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.