Description

(3Ar)-4α,8β-Bis(Acetyloxy)-3Aα,4,4Aα,7,8,8A,9,9Aβ-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical scaffolds. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents and exploring intricate chemical pathways.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex diterpenoids and other bioactive natural product analogs with potential therapeutic applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel drug candidates targeting various disease pathways.
• Organic Synthesis: Serves as a versatile chiral template or starting material for total synthesis projects in academic and industrial research settings.
• Biochemical Research: Potential use as a probe or inhibitor in studying specific enzymatic or biological processes due to its complex, functionalized structure.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for advanced material science and agrochemical research.

Basic Information

Item	Detail
Product Name	(3Ar)-4α,8β-Bis(Acetyloxy)-3Aα,4,4Aα,7,8,8A,9,9Aβ-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	13962-21-5
Molecular Formula	C21H26O6
Molecular Weight	374.43 g/mol
Synonyms	4α,8β-Diacetoxy-3aα,4,4aα,7,8,8a,9,9aβ-octahydro-5,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one; (3aR,4S,4aS,8S,8aR,9aS)-4,8-Diacetoxy-3a,4,4a,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one; Alantolactone diacetate derivative; Isoalantolactone diacetate (stereoisomer); Helenin derivative; Sesquiterpene lactone diacetate.
EINECS	Contact for details

Quality Control

Our (3Ar)-4α,8β-Bis(Acetyloxy)-3Aα,4,4Aα,7,8,8A,9,9Aβ-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.