Description

Tolfenamic Acid CAS NO 13710-19-5 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class. It serves as a critical pharmaceutical intermediate and reference standard in research and development. This compound is primarily utilized by manufacturers in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and by research institutions conducting pharmacological studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary NSAID medications and other therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of drug substances and products.
• Biochemical Research: Employed in pharmacological studies to investigate cyclooxygenase (COX) inhibition, anti-inflammatory pathways, and structure-activity relationships.
• Veterinary Medicine: Potential application in the development of anti-inflammatory treatments for animal health.
• Academic Research: Serves as a model compound in university and institutional research for teaching and experimental purposes.

Basic Information

Product Name	Tolfenamic Acid
CAS No.	13710-19-5
Molecular Formula	C14H12ClNO2
Molecular Weight	261.70 g/mol
Synonyms	2-[(3-Chloro-2-methylphenyl)amino]benzoic acid; N-(3-Chloro-2-methylphenyl)anthranilic acid; Tolfenamic acid; Tolfenamate; GEA 6414; Clotam; Migen; Tolfedine; Tolfine
EINECS	237-283-8

Quality Control

Our Tolfenamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.