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(2E)-3-(4-Bromophenyl)Acryloyl Chloride CAS NO 13565-09-8
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CAS No.:13565-09-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2E)-3-(4-Bromophenyl)Acryloyl Chloride is a high-purity, reactive organic intermediate featuring an acryloyl chloride moiety and a bromophenyl group. This compound is valued for its dual functionality, serving as a versatile building block for the synthesis of more complex molecules through reactions such as amidation, esterification, and cross-coupling. It is primarily sought after by research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and advanced materials sectors.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a brominated aromatic scaffold.
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromophenyl group imparts specific biological activity.
- Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialized polymers, liquid crystals, or organic electronic materials.
- Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex molecular architectures.
- Peptide Mimetics & Conjugation: The reactive acid chloride group is useful for coupling to amines, facilitating the creation of peptide analogs or bioconjugates.
- Dye & Pigment Manufacturing: Serves as an intermediate in the production of specialized dyes and organic pigments.
Basic Information
| Item | Details |
|---|---|
| Product Name | (2E)-3-(4-Bromophenyl)Acryloyl Chloride |
| CAS No. | 13565-09-8 |
| Molecular Formula | C9H6BrClO |
| Molecular Weight | 245.50 g/mol |
| Synonyms | 4-Bromocinnamoyl Chloride; (E)-3-(4-Bromophenyl)acryloyl chloride; trans-4-Bromocinnamoyl Chloride; 3-(4-Bromophenyl)-2-propenoyl Chloride; (2E)-3-(4-Bromophenyl)prop-2-enoyl Chloride; p-Bromocinnamoyl Chloride; 4-Bromo-trans-cinnamoyl Chloride; (E)-4-Bromocinnamoyl Chloride |
| EINECS | Contact for details |
Quality Control
Every batch of (2E)-3-(4-Bromophenyl)Acryloyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards where applicable, supporting its use in regulated environments.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, open flames, and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Related Substances (HPLC) | Individual impurity ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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