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(2E)-3-(4-Bromophenyl)Acryloyl Chloride CAS NO 13565-09-8


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CAS No.:13565-09-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2E)-3-(4-Bromophenyl)Acryloyl Chloride is a high-purity, reactive organic intermediate featuring an acryloyl chloride moiety and a bromophenyl group. This compound is valued for its dual functionality, serving as a versatile building block for the synthesis of more complex molecules through reactions such as amidation, esterification, and cross-coupling. It is primarily sought after by research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a brominated aromatic scaffold.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromophenyl group imparts specific biological activity.
  • Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialized polymers, liquid crystals, or organic electronic materials.
  • Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex molecular architectures.
  • Peptide Mimetics & Conjugation: The reactive acid chloride group is useful for coupling to amines, facilitating the creation of peptide analogs or bioconjugates.
  • Dye & Pigment Manufacturing: Serves as an intermediate in the production of specialized dyes and organic pigments.

Basic Information

Item Details
Product Name (2E)-3-(4-Bromophenyl)Acryloyl Chloride
CAS No. 13565-09-8
Molecular Formula C9H6BrClO
Molecular Weight 245.50 g/mol
Synonyms 4-Bromocinnamoyl Chloride; (E)-3-(4-Bromophenyl)acryloyl chloride; trans-4-Bromocinnamoyl Chloride; 3-(4-Bromophenyl)-2-propenoyl Chloride; (2E)-3-(4-Bromophenyl)prop-2-enoyl Chloride; p-Bromocinnamoyl Chloride; 4-Bromo-trans-cinnamoyl Chloride; (E)-4-Bromocinnamoyl Chloride
EINECS Contact for details

Quality Control

Every batch of (2E)-3-(4-Bromophenyl)Acryloyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards where applicable, supporting its use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, open flames, and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Water Content (KF) ≤ 0.5%
Related Substances (HPLC) Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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