Description

(2E)-3-(4-Methylphenyl)Acryloyl Chloride is a high-purity, reactive acid chloride derivative of p-methylcinnamic acid, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 4-methylcinnamoyl moiety into target molecules, facilitating the creation of complex chemical architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable and high-quality intermediate for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting metabolic and inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides where the cinnamoyl structure imparts biological activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with specific optical or mechanical properties.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing organic semiconductors and liquid crystal compounds.
• Peptide & Protein Modification: Utilized for acylating amino groups in peptides or biomolecules for research and diagnostic applications.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and pigments.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating novel chemical entities in academic and industrial R&D labs.

Basic Information

Item	Detail
Product Name	(2E)-3-(4-Methylphenyl)Acryloyl Chloride
CAS No.	13565-07-6
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	p-Methylcinnamoyl Chloride; (E)-3-(4-Methylphenyl)prop-2-enoyl chloride; 4-Methylcinnamoyl Chloride; trans-4-Methylcinnamoyl Chloride; 3-(4-Methylphenyl)-2-propenoyl Chloride; 4-Methyl-trans-cinnamoyl Chloride; (2E)-3-(4-Methylphenyl)-2-propenoyl Chloride; 4-Methylcinnamic Acid Chloride
EINECS	Contact for details

Quality Control

Our (2E)-3-(4-Methylphenyl)Acryloyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and titration for assay determination, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be stored in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to maximize shelf-life and maintain purity. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0 - 103.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.