Description

(E)-3-m-Tolyl-Acryloyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its core value lies in its acryloyl chloride functionality, which enables efficient acylation reactions to introduce the 3-methylcinnamoyl moiety into target molecules. This compound is critically needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its aromatic structure for bioactive molecule design.
• Polymer Chemistry: Serves as a monomer or cross-linking agent precursor for specialty polymers with tailored properties.
• Liquid Crystal & OLED Materials: A crucial intermediate for synthesizing advanced organic electronic materials and display components.
• Peptide Modification: Employed to acylate amino groups in peptides and proteins for biochemical studies and conjugate development.
• Dye & Pigment Manufacturing: Acts as a precursor for synthesizing complex organic dyes and high-performance pigments.

Basic Information

Product Name	(E)-3-m-Tolyl-Acryloyl Chloride
CAS No.	13565-04-3
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	(E)-3-(3-Methylphenyl)acryloyl chloride; trans-3-(m-Tolyl)acryloyl chloride; 3-(3-Methylphenyl)-2-propenoyl chloride; (E)-3-(3-Methylphenyl)-2-propenoyl chloride; m-Methylcinnamoyl chloride; (E)-m-Methylcinnamoyl chloride; 3-(m-Tolyl)acryloyl chloride; 2-Propenoyl chloride, 3-(3-methylphenyl)-, (E)-
EINECS	Contact for details

Quality Control

Every batch of (E)-3-m-Tolyl-Acryloyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our products are supported by comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Isomer Purity ((E)-isomer)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.