Description

Methyl 3-Bromo-6-Chloropyrazine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce halogenated pyrazine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with pyrazine-based active ingredients.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or semiconductors.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in fundamental research to explore new chemical reactions and develop novel heterocyclic compounds.

Basic Information

Product Name	Methyl 3-Bromo-6-Chloropyrazine-2-Carboxylate
CAS No.	13457-28-8
Molecular Formula	C6H4BrClN2O2
Molecular Weight	251.47 g/mol
Synonyms	Methyl 3-bromo-6-chloropyrazine-2-carboxylate; 3-Bromo-6-chloropyrazine-2-carboxylic acid methyl ester; Methyl 3-bromo-6-chloro-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 3-bromo-6-chloro-, methyl ester; 3-Bromo-6-chloro-2-pyrazinecarboxylic acid methyl ester; Methyl 3-bromo-6-chloro-pyrazine-2-carboxylate; 13457-28-8
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-6-Chloropyrazate-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality ensures the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.