Description

3α,7α-Dihydroxy-5β-Cholestan-26-Oic Acid Methyl Ester is a high-purity steroidal bile acid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is valued for its defined stereochemistry and functional groups, which are essential for the development of therapeutic agents targeting metabolic and liver-related pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates and diagnostic tools.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex therapeutic agents, particularly those targeting bile acid receptors and metabolic disorders.
• Biochemical Research: Used as a reference standard or precursor in studies of bile acid metabolism, liver function, and cholesterol homeostasis.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and clinical laboratories.
• Metabolic Pathway Studies: Employed in research to investigate enzymatic pathways and the biological activity of steroidal compounds.
• Academic & Industrial R&D: A vital reagent for universities and corporate R&D departments exploring new chemical entities and their biological effects.

Basic Information

Product Name	3α,7α-Dihydroxy-5β-Cholestan-26-Oic Acid Methyl Ester
CAS No.	13316-62-6
Molecular Formula	C₂₈H₄₈O₄
Molecular Weight	448.68 g/mol
Synonyms	Methyl 3α,7α-Dihydroxy-5β-cholestan-26-oate; Methyl 3α,7α-Dihydroxy-5β-cholestanoate; 5β-Cholestane-26-oic acid, 3α,7α-dihydroxy-, methyl ester; Chenodeoxycholic acid methyl ester derivative; 3α,7α-Dihydroxy-5β-cholestanoic acid methyl ester; Methyl 3α,7α-dihydroxy-5β-cholestanate
EINECS	Contact for details

Quality Control

Our 3α,7α-Dihydroxy-5β-Cholestan-26-Oic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles for pharmaceutical intermediates, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total area)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.