Description

Methyl 1-Methyl-4-Oxopiperidine-3-Carboxylate is a high-purity piperidine derivative and a versatile chiral building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with high stereochemical control, crucial for developing active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Peptidomimetic Scaffolds: Utilized in the design and synthesis of peptide mimics for biochemical and therapeutic applications.

Basic Information

Product Name	Methyl 1-Methyl-4-Oxopiperidine-3-Carboxylate
CAS No.	13221-89-1
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	1-Methyl-4-oxopiperidine-3-carboxylic acid methyl ester; Methyl 1-methyl-4-oxo-3-piperidinecarboxylate; 3-Piperidinecarboxylic acid, 1-methyl-4-oxo-, methyl ester; 1-Methyl-4-oxo-3-piperidinecarboxylic acid methyl ester; Methyl 1-methyl-4-oxonipecotate
EINECS	Contact for details

Quality Control

Our Methyl 1-Methyl-4-Oxopiperidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.