Description

(1α,2β,4α,6β)-2,6-Dimethylquinuclidine is a high-purity, stereochemically defined bicyclic tertiary amine, serving as a critical chiral building block and ligand in advanced organic synthesis. Its rigid quinuclidine scaffold and specific stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial control. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets.
• Asymmetric Catalysis: Employed as a chiral ligand or catalyst component in enantioselective transformations, such as hydrogenations and C-C bond formations.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study enzyme mechanisms and receptor interactions.
• Material Science: A precursor for functionalized polymers and advanced organic materials requiring specific molecular geometry.
• Academic & Process R&D: A valuable tool for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(1α,2β,4α,6β)-2,6-Dimethylquinuclidine
CAS No.	13218-10-5
Molecular Formula	C9H17N
Molecular Weight	139.24 g/mol
Synonyms	(1R,2S,4R,6S)-2,6-Dimethyl-1-azabicyclo[2.2.2]octane; (1R,2S,4R,6S)-2,6-Dimethylquinuclidine; (1alpha,2beta,4alpha,6beta)-2,6-Dimethylquinuclidine; 2,6-Dimethylquinuclidine (stereoisomer); Quinuclidine, 2,6-dimethyl-, (1R,2S,4R,6S)-; Bicyclic tertiary amine ligand
EINECS	Contact for details

Quality Control

Our (1α,2β,4α,6β)-2,6-Dimethylquinuclidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and stereochemical composition is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.