Description

2-Linoleoyl-1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine is a defined, high-purity phospholipid, specifically a phosphatidylethanolamine (PE), with a mixed fatty acid chain composition. This compound is critical for research and development in advanced lipid-based delivery systems due to its role as a fundamental component of biological membranes. It is essential for scientists and manufacturers in the pharmaceutical, nutraceutical, and advanced material sectors who require precise lipid building blocks for liposome formulation, membrane biophysics studies, and the development of lipid nanoparticles (LNPs).

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, biocompatible vesicles for drug and gene delivery.
• Membrane Biophysics Research: Used as a standard or model lipid to study membrane fluidity, phase behavior, and protein-lipid interactions.
• Cell Culture & Biochemistry: Employed in synthetic lipid supplements to create defined media conditions or to study cellular signaling pathways.
• Pharmaceutical Excipient Development: Serves as a functional raw material in developing advanced parenteral and topical dosage forms.
• Nutraceutical Encapsulation: Used to create liposomal delivery systems for vitamins, antioxidants, and other sensitive bioactive compounds to enhance bioavailability.
• Diagnostic Reagent Preparation: A component in the formulation of reagents for clinical diagnostics and analytical assays.

Basic Information

Product Name	2-Linoleoyl-1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	13206-00-3
Molecular Formula	C41H76NO8P
Molecular Weight	742.02 g/mol
Synonyms	1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine; PE(16:0/18:2); PLPE; Phosphatidylethanolamine (16:0/18:2); (2R)-2,3-Bis[[(9Z,12Z)-octadeca-9,12-dienoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; L-α-Phosphatidylethanolamine, 1-palmitoyl-2-linoleoyl-; 1-Hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine
EINECS	Contact for details

Quality Control

Every batch of our 2-Linoleoyl-1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical applications. Certificates of Analysis (COA) detailing specifications such as assay, fatty acid profile, and impurity limits are available upon request. Our quality commitment supports compliance with relevant guidelines for research and cGMP-grade material production.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Fatty Acid Composition (GC)	Conforms to Palmitoyl & Linoleoyl profile
Water Content (KF)	≤ 3.0%
Peroxide Value	≤ 5.0 meq/kg
Solvent Residues (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.