Description

1-Palmitoylphosphatidylethanolamine is a high-purity, synthetic phospholipid, specifically a lysophospholipid, that serves as a critical building block in lipid research and formulation. This compound is essential for studying membrane biophysics, creating model lipid bilayers, and developing advanced lipid-based delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for applications ranging from drug delivery to cosmetic science.

Application

• Lipid Nanoparticle (LNP) Formulation: A key component in the development of mRNA and siRNA delivery vehicles.
• Liposome & Niosome Production: Used as a structural lipid to create stable vesicles for targeted drug delivery and cosmetic actives encapsulation.
• Biomembrane Research: Essential for constructing model cell membranes to study protein-lipid interactions, permeability, and fusion processes.
• Cell Culture & Transfection Reagents: Incorporated into lipid mixtures to enhance the efficiency of introducing nucleic acids into cells.
• Diagnostic Assay Development: Used in the fabrication of biosensors and diagnostic platforms that mimic natural membrane environments.
• Cosmetic Formulations: Acts as a skin-identical lipid and emulsifier in high-end skincare products for improved barrier function and active ingredient delivery.

Basic Information

Item	Detail
Product Name	1-Palmitoylphosphatidylethanolamine
CAS No.	13190-01-7
Molecular Formula	C21H44NO7P
Molecular Weight	453.55 g/mol
Synonyms	1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; 16:0 Lyso PE; Lyso-PE (16:0); Palmitoyl Lyso-phosphatidylethanolamine; 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; LPE (16:0/0:0); sn-Glycero-3-phosphoethanolamine-N-(1-palmitoyl); Lysophosphatidylethanolamine (16:0)
EINECS	Contact for details

Quality Control

Our 1-Palmitoylphosphatidylethanolamine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, desiccate to minimize moisture uptake. Allow the product to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Solubility	Soluble in chloroform, methanol, ethanol; forms micelles in water
Heavy Metals	< 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.