Description

Piperazine-2,3-Dione is a high-purity heterocyclic organic compound, also known as 2,3-diketopiperazine, which serves as a fundamental building block in advanced organic synthesis. Its rigid, cyclic diamide structure makes it a valuable precursor and scaffold for the development of pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and production in the pharmaceutical industry, particularly for creating peptidomimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, including kinase inhibitors and protease inhibitors.
• Peptidomimetic Scaffold: Used in medicinal chemistry to create stable, bioavailable analogs of peptide drugs.
• Agrochemical Research: Serves as a core structure in developing new herbicides and fungicides.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for creating chiral ligands and catalysts.
• Polymer Modification: Acts as a monomer or cross-linking agent for specialty polymers with enhanced thermal properties.
• Academic & Industrial R&D: A fundamental reagent for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	Piperazine-2,3-Dione
CAS No.	13092-86-9
Molecular Formula	C4H6N2O2
Molecular Weight	114.10 g/mol
Synonyms	2,3-Diketopiperazine; Diketopiperazine; DKP; 2,3-Piperazinedione; Cyclo(Gly-Gly); 1,4-Diazinane-2,3-dione; Glycine anhydride
EINECS	Contact for details

Quality Control

Our Piperazine-2,3-Dione is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades, including research and pharmaceutical intermediates, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.