Description

6-Acetyloxy-3A,3B,4,4A,4B,5,6,7,7A,7B-Decahydro-7A-Hydroxy-4A,7-Dimethyl-3-Methylenecycloprop[6,7]Indeno[4,5-B]Furan-2(3H)-One is a complex, high-purity sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules and complex natural product analogs. It is primarily sought after by research institutions and pharmaceutical development teams engaged in medicinal chemistry, process R&D, and the exploration of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for complex molecular scaffolds.
• Natural Product Synthesis: Serves as a pivotal intermediate in the total or semi-synthesis of sesquiterpene-based natural products.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP-like conditions.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological pathways and target validation.
• Academic Research: Fundamental studies in organic synthesis methodology and complex molecule construction.

Basic Information

Product Name	6-Acetyloxy-3A,3B,4,4A,4B,5,6,7,7A,7B-Decahydro-7A-Hydroxy-4A,7-Dimethyl-3-Methylenecycloprop[6,7]Indeno[4,5-B]Furan-2(3H)-One
CAS No.	13048-24-3
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	6-Acetoxy-3a,3b,4,4a,4b,5,6,7,7a,7b-decahydro-7a-hydroxy-4a,7-dimethyl-3-methylidenecyclopropa[6,7]indeno[4,5-b]furan-2(3H)-one; 6α-Acetoxy-7α-hydroxyvouacapen-5β-oic acid γ-lactone; 6-Acetoxy-7-hydroxyvouacapen-5-oic acid γ-lactone; Vouacapen-5-oic acid, 6-acetoxy-7-hydroxy-, γ-lactone; A derivative of vouacapane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ HPLC, GC, NMR, and MS for characterization, ensuring the material meets the exacting standards required for pharmaceutical R&D and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.